Isolation, crystal structure determination and cholinesterase inhibitory potential of isotalatizidine hydrate from Delphinium denudatum
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چکیده
منابع مشابه
Bioactive constituent of Delphinium denudatum Wall. and their Antioxidant efficacy
Delphinium denudatum known as Jadwar, is critically enlarged Himalayan herbs, which was once commonest species. It is distinguished by its relatively small blue or violet color and it is one of the important drugs used as indigenous medicine in India, especially in Unani medicine system. A number of studies have been done on its phytochemical and pharmacological properties. Bioactive constituen...
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Ciprofloxacin belongs to a family of quinolone antibacterial agents. The crystal structure of ciprofloxacin hydrochloride 1,34-hydrate was determined. Most of the bond lengths and angles of the ciprofloxacin cation are very similar to those of ciprofloxacin hexahydrate, which appears in the zwitterionic form. The exceptions are the carbon-oxygen bond distances in the carboxylic group, since in ...
متن کاملProtective role of Delphinium denudatum (Jadwar) against morphine induced tolerance and dependence in mice.
Chronic treatment with Delphinium denudatum (Dd) (Jadwar) (family: Ranunculaceae, 200-1600 mg/kg) suppressed morphine withdrawal jumps in a dose-dependent manner, a sign of the development of dependence to opiate as assessed by naloxone (2 mg/kg) precipitation withdrawal on day 10 of testing in mice. Repeated administration of Dd (200-1600 mg/kg) for 9 days attenuated the development of toleran...
متن کاملIn Vivo Psychopharmacological Investigation of Delphinium Denudatum and Amaranthus Spinosus Extracts on Wistar Rats
Introduction: In our modern era, life style of human being changes and updates every day that may affect their health status. There is an incredible expectation that natural origin drugs lack undesirable effects not like synthetic drugs, though have the same potency and efficacy. No scientific data is available about the antianxiety properties of Delphinium denudatum root and Amaranthus spinosu...
متن کاملExperimental study of the morphine de-addiction properties of Delphinium denudatum Wall.
BACKGROUND Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. METHODS Charles Foster male albino rats were made morphine dependent by injecting morphine sulphate in increasing doses twice a day for 7 days. The spontaneous withdrawal signs observed 12 h after the last dose were quantified by the 'counted' and 'checked' signs. The drug (...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2016
ISSN: 1388-0209,1744-5116
DOI: 10.1080/13880209.2016.1240207